Searching for Useful Substances in Nature
Uncovering novel compounds for pesticides and pharmaceuticals derived from marine life!
Marine organisms are a treasure trove of substances with unique structures and potent biological activities. Our group integrates research in organic chemistry and life sciences to discover novel compounds. Examples include food poisoning agents from bivalves, anticancer substances from mollusks, and anti-inflammatory substances from sponges, which have potential as pesticides and pharmaceuticals. We are dedicated to elucidating the mechanisms of action of these compounds.
Exploration and Application of Natural Products Binding to the Third Life Chain: Glycans
Glycans are molecules formed by the chain-like linkage of monosaccharides such as glucose. Recently, glycans have been shown to possess diverse biological functions, drawing attention as the "third chain of life" alongside nucleic acids (chains of nucleotides) and proteins (chains of amino acids). Our group is exploring natural products that bind glycans, with the aim of applying this research to drugs for glycans-related infectious diseases, such as antifungal and antiviral agents.